Topic: Study Reveals Paget?s Disease Prevalent in Lupine Hybrids

Darien Fenner

Date: 2010-03-26 17:19 EST
The following article was seen on page twelve of the RhyDin Post, March the twenty-fifth.

http://i738.photobucket.com/albums/xx21/dfenner_photo/handsomedoctor.jpg RhyDin Health Journalist: Dr. Arshad Herat

Study Reveals Paget's Disease Prevalent in Lupine Hybrids March 25, 2010

A new study by patholigists at Old Town Private University may have demonstrated an increased pervasiveness of Paget's disease among lupine and canine humanoids in concurrence with canine distemper virus (CDV).

Paget's disease is a primarily human-borne condition characterized by the improper formation of bone due to irregular homeostatic calcium levels in the blood. Complications of the condition can lead to enlarged and misshapen bone, pain and stiffness in diarthrotic joints, and congestive heart failure. While genes have recently been associated with Paget's disease, more evidently, certain viruses have been found to trigger the mutation of the gene and cause development of the condition.

According to a double-blind study done by the university's health department, scientists have found that an etiopathic relationship exists between the development of the bone condition and unvaccinated canine species and subspecies.

Using a reverse transcriptase-polymerase chain reaction method, (RT-PCR) scientists have isolated the presence of the CDV nucleocaspid ribonucleic acid in fifty-five percent of pagetic bone.

Canine distemper is a viral disease native to Class M planets that generally afflicts animals and hybrids from the families Canidae, Mustelidae, and Hyaenidae, though it has been known to blight members of the Felidae family as well. Complications of CDV can lead to pneumonia, encephalitis, and vestibular disease, which can directly affect the sense of balance and spatial orientation.

According to the department head, Dr. Limel Cinista, secondary vaccination for CDV produces no change in Paget's patients.

"While our in-situ PCR method has isolated consistent cases of Paget's disease in concurrence with distemper, it's really kind of impossible to anticipate a cure at this point," said Cinista. "The most successful treatment for distemper is, of course, prevention. If canine and lupine patients remain unvaccinated, the autoimmune response that comes as a consequence of CDV could very well trigger much more serious genetic conditions. The lesson here is merely to ensure that you are up to date on all your vaccinations. An ounce of prevention is worth a pound of cure."

In related news, Paget's sarcoma, a rare form of osteosarcoma that occurs in about 5% of patients with advanced polyostotic Paget's disease, was found to be virtually non-existent in canine and lupine hybrids.