In the middle of present-day Syrian desert, Juliana and Imad have found another ingredient on a list that was given to her by Titus, twenty years before his death. He told her that it was a recipe to create a cure for vampirism and that it had been handed down by vampires of his line for thousands of years. After collecting the ingredient?oak galls from trees that grow in the Anti-Lebanon mountains?Juliana and Imad return to Denver, which is where Juliana lives.
In a flashback scene, to 1500's Seville, we learn that Juliana made a vampire childe, a tailor from Cadiz called Noah Hyatt. They were very much in love with each other and enjoyed their existence together for nearly 100 years.
In Denver, Juliana and Imad continue their research and find the second to last ingredient in the Gobi desert of northwestern China. Juliana arranges a expedition to the area, leaving Imad in Denver to continue researching the last ingredient. While Juliana is in China, she received a phone call from Detective Charlie Dekker, of the Denver police. Charlie explains to Juliana that Imad has been murdered and Juliana immediately returns to Denver.
In another flashback scene, again to sixteenth century Spain, Juliana returns to a comfortable villa in the surrounding countryside of Seville. It's at night and the front door of the villa has been smashed in. As Juliana moves through the house, it becomes apparent that someone has broken in and destroyed much of the furniture and artwork the couple had collected throughout their time together. Repeated calls for Noah go unanswered and finally when Juliana enters their bedchamber, she finds Noah's headless body arranged on their bed, with his hand held between his hands. She also finds his murderer, her first childe, a man she saved from the Black Death in 14th century England, called Crispin Cooper.
We see how Juliana finds Crispin lying near death in his family's hovel and turns him into a vampire. Crispin is not entirely sane and a series of grisly murders turns out to be his doing. In order to protect the people of London, Juliana agrees to be Crispin's slave, doing anything he wants to her, so long as he leaves the city alone. He readily agrees and for the next 20 years, he is satisfied with the arrangement. Once word of Columbus's discovery of the West Indies reaches London, however, Crispin succumbs to wanderlust. He wants to mount an expedition and Juliana willingly and readily gives him money to buy a ship and crew of his own. The last we see of Crispin is when he's sailing towards America.
Back in Denver now, Juliana has her first interview with Charlie. He asks tough questions and when he tells her that Imad's body had been completely drained of blood, Juliana immediately realizes that a vampire has murdered him. Charlie feels that Juliana knows more than she's saying, but doesn't know exactly what.
Juliana continues Imad's research, finding the last ingredient in Russia. She goes and collects it and comes back to Denver, only to discover that three of the scholars she has previously contacted about her research have been killed in the same way as Imad. Juliana begins to suspect that Crispin is responsible and her suspicions are confirmed when he shows up in her home. He tells her that he doesn't want her to take the cure; he'll kill everyone involved with her research and the formula. Juliana insists that she's tired of existing; she's existed for over a thousand years and wants peace. Crispin calls her weak and they get into a fight, smashing furniture and screaming at each other.
Charlie, who has been following Juliana and digging into her past is parked out in front of her apartment, overhears a radio call about an intruder in the building, phoned in by one of Juliana's neighbours who was awoken by the loud crashes and screams. He races up to Juliana's apartment and gets into a fight with Crispin, who tosses Charlie through a plate-glass window out onto a balcony, before leaping over the side of the building, landing on the street five floors below and racing away in the night.
When Charlie was tossed through the window, a shard of glass opened his inner arm from wrist to elbow and he is bleeding heavily. Juliana gives him some of her blood and then glamours him into forgetting about his wound as well as Juliana healing him. Charlie's backup officers arrive on the scene and Charlie recounts what he thinks he remembers about the suspect and the fight and then stays with Juliana in her apartment for the rest of the night.
A week later, Charlie calls Juliana and invites her out on a date. They go to a French film and then out for a drink at a local bar. Charlie drives Juliana back to her apartment and kisses her goodnight. She invites him in and they go to bed together. Crispin, who has also been following Juliana, witnesses this and tries to attack Charlie the next morning, but is interrupted by Juliana's arrival.
Juliana cannot glamour Charlie again and so she levels with him and proves to him that she is a vampire. She tells him about the cure and he vows to keep her safe until she can complete and take it. Crispin comes back to her apartment just after she has finished the cure and she and Charlie kill him.
Juliana takes the cure and learns that it isn't actually a cure, but more of a curse. It turns vampires into mindless, insatiable killing machines. Juliana goes on a killing spree in a night club and when she's finally cornered by the police, Charlie responds to the call. She begs Charlie to kill her. He does and the final scene in the movie is of Charlie tossing the recipe for the 'cure' onto Juliana's funeral pyre.
In a flashback scene, to 1500's Seville, we learn that Juliana made a vampire childe, a tailor from Cadiz called Noah Hyatt. They were very much in love with each other and enjoyed their existence together for nearly 100 years.
In Denver, Juliana and Imad continue their research and find the second to last ingredient in the Gobi desert of northwestern China. Juliana arranges a expedition to the area, leaving Imad in Denver to continue researching the last ingredient. While Juliana is in China, she received a phone call from Detective Charlie Dekker, of the Denver police. Charlie explains to Juliana that Imad has been murdered and Juliana immediately returns to Denver.
In another flashback scene, again to sixteenth century Spain, Juliana returns to a comfortable villa in the surrounding countryside of Seville. It's at night and the front door of the villa has been smashed in. As Juliana moves through the house, it becomes apparent that someone has broken in and destroyed much of the furniture and artwork the couple had collected throughout their time together. Repeated calls for Noah go unanswered and finally when Juliana enters their bedchamber, she finds Noah's headless body arranged on their bed, with his hand held between his hands. She also finds his murderer, her first childe, a man she saved from the Black Death in 14th century England, called Crispin Cooper.
We see how Juliana finds Crispin lying near death in his family's hovel and turns him into a vampire. Crispin is not entirely sane and a series of grisly murders turns out to be his doing. In order to protect the people of London, Juliana agrees to be Crispin's slave, doing anything he wants to her, so long as he leaves the city alone. He readily agrees and for the next 20 years, he is satisfied with the arrangement. Once word of Columbus's discovery of the West Indies reaches London, however, Crispin succumbs to wanderlust. He wants to mount an expedition and Juliana willingly and readily gives him money to buy a ship and crew of his own. The last we see of Crispin is when he's sailing towards America.
Back in Denver now, Juliana has her first interview with Charlie. He asks tough questions and when he tells her that Imad's body had been completely drained of blood, Juliana immediately realizes that a vampire has murdered him. Charlie feels that Juliana knows more than she's saying, but doesn't know exactly what.
Juliana continues Imad's research, finding the last ingredient in Russia. She goes and collects it and comes back to Denver, only to discover that three of the scholars she has previously contacted about her research have been killed in the same way as Imad. Juliana begins to suspect that Crispin is responsible and her suspicions are confirmed when he shows up in her home. He tells her that he doesn't want her to take the cure; he'll kill everyone involved with her research and the formula. Juliana insists that she's tired of existing; she's existed for over a thousand years and wants peace. Crispin calls her weak and they get into a fight, smashing furniture and screaming at each other.
Charlie, who has been following Juliana and digging into her past is parked out in front of her apartment, overhears a radio call about an intruder in the building, phoned in by one of Juliana's neighbours who was awoken by the loud crashes and screams. He races up to Juliana's apartment and gets into a fight with Crispin, who tosses Charlie through a plate-glass window out onto a balcony, before leaping over the side of the building, landing on the street five floors below and racing away in the night.
When Charlie was tossed through the window, a shard of glass opened his inner arm from wrist to elbow and he is bleeding heavily. Juliana gives him some of her blood and then glamours him into forgetting about his wound as well as Juliana healing him. Charlie's backup officers arrive on the scene and Charlie recounts what he thinks he remembers about the suspect and the fight and then stays with Juliana in her apartment for the rest of the night.
A week later, Charlie calls Juliana and invites her out on a date. They go to a French film and then out for a drink at a local bar. Charlie drives Juliana back to her apartment and kisses her goodnight. She invites him in and they go to bed together. Crispin, who has also been following Juliana, witnesses this and tries to attack Charlie the next morning, but is interrupted by Juliana's arrival.
Juliana cannot glamour Charlie again and so she levels with him and proves to him that she is a vampire. She tells him about the cure and he vows to keep her safe until she can complete and take it. Crispin comes back to her apartment just after she has finished the cure and she and Charlie kill him.
Juliana takes the cure and learns that it isn't actually a cure, but more of a curse. It turns vampires into mindless, insatiable killing machines. Juliana goes on a killing spree in a night club and when she's finally cornered by the police, Charlie responds to the call. She begs Charlie to kill her. He does and the final scene in the movie is of Charlie tossing the recipe for the 'cure' onto Juliana's funeral pyre.